Endocrine Disruptors

Eurofins offers the full Tier 1 battery of tests in included in the EPA’s Endocrine Disruptor Screening Program (EDSP, dated 10-21-2009) and we are also able to conduct all of the Tier 2 requirements.

Tier 1 Complete Battery of Services:

In vitro

  • Estrogen receptor (ER) binding – rat uterine cytosol
  • Estrogen receptor (hERα) transcriptional activation – Human cell line (HeLa-9903)
  • Androgen receptor (AR) binding – rat prostate cytosol
  • Steroidogenesis – Human cell line (H295R)
  • Aromatase – Human recombinant microsomes

In vivo

  • Uterotrophic (rat)
  • Hershberger (rat)
  • Pubertal female (rat)
  • Pubertal male (rat)
  • Amphibian metamorphosis (frog)
  • Fish short-term reproduction

Click here to find more information about Endocrine Disruptor services that Eurofins can offer.