Cardiovascular

Disease State or Symptom Animal Model or Test System
Myocardial Ischemia Coronary Artery Occlusion/Ligation-Dog, Rat
Cerebral Ischemia Rat Middle Cerebral Arterry Occlusion
Septic Shock Cecal Ligation, Bacterial Injection, Endotoxin-Rats
Hemorrhage Wiggers Mice
Heart Failure Ischemia-Induced Heart Failure in the Rat
Hypertension Spontaneously Hypertensive Rat
Atherosclerosis High Cholesterol-Fed Rabbits, Watanabe Rabbits
ApoE Knockout Mice
Stroke/ Cerebral Ischemia Middle Cerebral Artery Occlusion-Rat

PSL can test compounds for their acute or long term effects on arterial blood pressure, heart rate, ECG in rats, mice, rabbits, dogs and primates. We also have considerable experience in the evolution of cardiovascular devices.