Central Nervous System
| Disease State or Symptom | Animal Model or Test System |
| Behavioral Activity | Irwin Screen Rat or Mouse Spontaneous motor activity - Mouse Rotarod - Mouse |
| Anti-Convulsant Activity | Anti-Metrazole Seizure test - Mouse |
| Pain | Acetylcholine / Acetic Acid-Induced Writhing - Mouse Hot plate - Mouse Tail flick - Mouse Hot Water -Tail dip - Mouse |
| Post-Operative Pain | Incisional Pain - Mouse, Rat |
| Insomnia | Sleep time - Mouse, Rat |
| Nausea and Vomiting | Induced vomiting - Ferret |
| Parkinsonism | Catalepsy - Mouse |
| Pruritis | Mouse |
| Neuropathic Pain | Spinal Nerve Ligation - Rat, Mouse Chronic Constriction Injury - Rat, Mouse Partial Sciatic Nerve Ligation - Rat, Mouse Cuff - Rat Crush - Rat, Mouse |
Our behavioral pharmacologists are experienced in a variety of assays to screen experimental compounds against industry standards and evaluate their efficacy in the above models. Let us know your area of interest and we can develop a testing strategy that would suit your needs.
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