Gastrointestinal
| Disease State or Symptom | Animal Model or Test System |
| Fecal Propulsion | Colonic Propulsion Velocity - Guinea Pig |
| Peptic Ulcer | Pylorus Ligated Rat |
| Gastric or Intestinal Hemorrhage | Gastric or Intestinal hemorrhage -Rat Prevention of Induced Gastric or Intestinal Lesions |
| Post-operative Ileus | Charcoal Meal Test - Rat |
| Gastroparesis | Charcoal Meal Test - Rat Gastric Emptying - Polystyrene bead test Rat |
| Constipation | Fecal Pellet Output - Mouse, Rat |
| Visceral Pain, Irritable Bowel Syndrome | Glass Bead test - Mouse |
| Inflammatory Bowel Disease | Dextran Sulfate Sodium induced colitis- Mouse |
| Diarrhea | Prevention of Induced diarrhea - Rat, Mouse |
| Hypersecretory Diarrhea | Pylorus - Ileal Ligated Rat |
| Nausea and Vomiting | Induced Emesis/Vomiting - Ferret Antagonism of induced emesis/vomiting - Ferret |
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