Metabolic Diseases

Disease State or Symptom Animal Model or Test System
Dyslipidemia Cholesterol-Fed Rats,Hamsters and Primates, fa-fa Rats, ob/ob Mice
Diabetes, Obesity, Metabolic Syndrome Diet-Induced Obesity - C57BL/6J Mouse
Zucker Fatty Rats (non-diabetic)
db/db Mouse
Zucker Diabetic Rat
Streptozocin-Induced Hyperglycemic Rat

In any of the above models, or in a custom designed protocol, PSL can evaluate, as desired:

  1. Glucose
  2. Insulin
  3. Glucose tolerance-oral or iv
  4. Triglycerides
  5. Total cholesterol, HDL and LDL
  6. Body weight, weight loss
  7. Food consumption
  8. Body composition (DEXA)