PSL >> Pharmacology >> Gastrointestinal


Disease State or Symptom

Animal Model or Test System


Sensitization/anaphalaxis - Guinea Pig

Fecal Propulsion

Colonic Propulsion Velocity - Guinea Pig

Peptic Ulcer

Pylorus Ligated Rat

Gastric or Intestinal Hemorrhage

Gastric or Intestinal hemorrhage -Rat
Prevention of Induced Gastric or Intestinal Lesions

Post-operative Ileus

Charcoal Meal Test - Rat


Charcoal Meal Test - Rat
Gastric Emptying - Polystyrene bead test Rat


Fecal Pellet Output - Mouse, Rat

Visceral Pain, Irritable Bowel Syndrome

Glass Bead test - Mouse

Inflammatory Bowel Disease

Dextran Sulfate Sodium induced colitis- Mouse


Prevention of Induced diarrhea - Rat, Mouse

Hypersecretory Diarrhea

Pylorus - Ileal Ligated Rat

Nausea and Vomiting

Induced Emesis/Vomiting - Ferret
Antagonism of induced emesis/vomiting - Ferret