PSL >> Pharmacology >> Metabolic Diseases

Metabolic Diseases

Disease State or Symptom

Animal Model or Test System


Cholesterol-Fed Rats,Hamsters and Primates, fa-fa Rats, ob/ob Mice

Diabetes, Obesity, Metabolic Syndrome

Diet-Induced Obesity - Mice, Rats
Zucker Fatty Rats (diabetic or non-diabetic)
db/db Mouse
Streptozocin-Induced Hyperglycemic Rat

In any of the above models, or in a custom designed protocol, Product Safety Labs can evaluate, as desired:

  1. Blood glucose
  2. Hemoglobin glycation (Hb A1c)
  3. Insulin
  4. Glucose tolerance-oral, ip
  5. Triglycerides
  6. Total cholesterol, HDL and LDL
  7. Body weight, weight loss
  8. Food consumption
  9. Body composition (DEXA)
  10. Target organ histopathology
  11. Circulating hormones and peptides